Nootropics

Adaptogens

Cannabis:

  • Health
  • Medicinal Properties
  • The History
  • Preparing
  • The Right Strain 

Cannabis is a topic that has varying legal status across different regions. Let’s explore the current situation:

  1. Cannabis is a topic that has varying legal status across different regions. Let’s explore the current situation:

    1. United States:

    2. CBD (Cannabidiol):

  • The global legal cannabis market size was valued at USD 22.1 billion in 2022 and is expected to expand at a compound annual growth rate (CAGR) of 25.5% from 2023 to 2030

The cannabis or hemp plant originally evolved in Central Asia before people introduced the plant into Africa, Europe, and eventually the Americas1. Hemp fiber was used to make clothing, paper, sails, and rope, and its seeds were used as food1. Because it’s a fast-growing plant that’s easy to cultivate and has many uses, hemp was widely grown throughout colonial America and at Spanish missions in the Southwest1. In the early 1600s, the Virginia, Massachusetts, and Connecticut colonies required farmers to grow hemp1.

There’s some evidence that ancient cultures knew about the psychoactive properties of the cannabis plant. They may have cultivated some varieties to produce higher levels of THC for use in religious ceremonies or healing practice1. Burned cannabis seeds have been found in the graves of shamans in China and Siberia from as early as 500 BC1.

In the 1830s, Sir William Brooke O’Shaughnessy, an Irish doctor studying in India, found that cannabis extracts could help lessen stomach pain and vomiting in people suffering from cholera1. By the late 1800s, cannabis extracts were sold in pharmacies and doctors’ offices throughout Europe and the United States to treat stomach problems and other ailments1.

The earliest restrictions on cannabis were reported in the Islamic world by the 14th century2. In the 19th century, it began to be restricted in colonial countries, often associated with racial and class stresses2. In the middle of the 20th century, international coordination led to sweeping restrictions on cannabis throughout most of the globe2. Entering the 21st century, some nations began to take measures to decriminalize or legalize cannabis2.

Terpenes are naturally occurring chemical compounds found in plants, including cannabis. They play a crucial role in the aroma, flavor, and effects of various vegetation. Here’s what you need to know:

  1. What Are Terpenes?

  2. Role of Terpenes:

  3. Psychoactivity and Terpenes:

  4. Comparison to THC and CBD:

In summary, terpenes are the aromatic and flavorful components of cannabis, working alongside cannabinoids to create the diverse effects we associate with different strains. 

Adaptogens are herbs, roots and other plant substances (like mushrooms) that help our bodies manage stress and restore balance after a stressful situation. People take adaptogens as herbal supplements in capsule form, drink them in teas or in a powder added to soups, smoothies and other foods

Nootropics, also known as “smart drugs” in English language journals [], are a heterogeneous group of compounds. The term “nootropic” was first used by Cornelius E. Giurgea in 1972/1973  to describe substances that primarily activate cognitive functions, such as memory and learning, especially in situations where these functions are impaired. In a sense, they interfere with the metabolism of neuronal cells of the central nervous system (CNS). The name consists of two Greek words: nöos, which means thinking, and tropein, which means to guide. There is no uniform approach to categorizing these compounds. Some authors distinguish between classical nootropics and substances that enhance brain metabolism, while others combine these two groups, or use the term cognitive effect rather than nootropic.Cannabis use is legal in California. But cities and counties can prohibit cannabis businesses, like retail. As a result, the state is a patchwork of areas where it is and is not legal to establish a cannabis business.

Nootropics do not act directly by releasing neurotransmitters or as receptor ligands, but improve the brain’s supply of glucose and oxygen, have antihypoxic effects, and protect brain tissue from neurotoxicity. They also positively affect neuronal protein and nucleic acid synthesis and stimulate phospholipid metabolism in neurohormonal membranes. Some nootropics have been found to affect the elimination of oxygen free radicals, possess an anti-aggregation effect, and improve erythrocyte plasticity. This improves the rheological properties of the blood and improves blood flow to the brain. These substances are metabolically active, but most nootropics show no immediate effects after a single dose, requiring an extended period of use to produce results. They need to be able to penetrate the blood–brain barrier to improve brain metabolism and long-term use is necessary to achieve stable changes.

Finding the right cannabis strain based on terpene profiles involves understanding the unique characteristics of different terpenes and their potential effects. Here are steps to guide you:

  1. Learn About Terpenes:

    • Familiarize yourself with common terpenes found in cannabis. Some popular ones include:
      • Limonene: Known for its citrus scent, it may have uplifting and stress-relieving effects.
      • Myrcene: Associated with sedation and relaxation.
      • Pinene: Smells like pine and may enhance focus and alertness.
      • Caryophyllene: Has a spicy aroma and may have anti-inflammatory properties.
      • Linalool: Floral scent, potentially calming and helpful for sleep.
    • Research other terpenes to understand their unique qualities.
  2. Identify Your Desired Effects:

    • Consider what you’re looking for in a strain. Are you seeking relaxation, creativity, pain relief, or energy?
    • Match terpenes to your desired effects. For example:
      • If you want relaxation, look for strains high in myrcene or linalool.
      • For focus, seek strains with pinene.
      • If you need mood elevation, limonene-rich strains might be suitable.
  3. Explore Strain Profiles:

    • Visit dispensaries or online platforms that provide detailed strain information.
    • Look for strains with terpene profiles aligned with your preferences.
    • Read user reviews to learn about real-world experiences.
  4. Experiment Gradually:

    • Start with small quantities of different strains.
    • Keep a journal to track how each strain affects you.
    • Note the terpene content and any specific effects you experience.
  5. Consult with Experts:

    • Talk to budtenders at dispensaries. They can recommend strains based on your preferences.
    • Seek advice from medical professionals if you have specific health concerns.

Remember that everyone’s response to cannabis is unique. Trial and error will help you find the strain that suits your needs best. Happy exploring! 

There are many ways to use cannabis, such as smoking, vaping, eating, or applying topically. Each method has its own benefits and drawbacks, and may affect you differently depending on your personal factors, such as your tolerance, metabolism, and health conditions. Here are some general tips to help you prepare to use cannabis safely and responsibly:

  • Choose the right strain and product for your desired effects. Cannabis strains can be classified into three main types: indica, sativa, and hybrid. Indica strains tend to have relaxing and sedating effects, while sativa strains tend to have uplifting and energizing effects. Hybrid strains are a mix of both, and can vary in their effects depending on the ratio of indica to sativa. You can also look at the cannabinoid content of the product, such as THC and CBD, which are the main compounds that produce the psychoactive and therapeutic effects of cannabis. THC is responsible for the high, while CBD is non-intoxicating and can counteract some of the negative effects of THC, such as anxiety and paranoia. You can ask a budtender at a licensed dispensary to help you find the best product for your needs1
  • Start low, go slow, and stay low. This means that you should start with a low dose, wait for the effects to kick in, and avoid taking more until you know how you react. This is especially important for edibles, which can take up to two hours to take effect, and can last much longer than smoking or vaping. Edibles also have a higher chance of causing unpleasant side effects, such as nausea, drowsiness, and impaired coordination. A standard dose of edibles is 10 mg of THC, but beginners may want to start with half or even a quarter of that345.
  • Be in a comfortable and safe environment. Using cannabis can alter your perception, mood, and behavior, so it is important to be in a place where you feel relaxed and secure. Avoid using cannabis in public places, driving, or operating heavy machinery. It is also advisable to have a sober and trusted friend with you, especially if you are trying cannabis for the first time or using a new product. They can help you in case you experience any adverse effects or need assistance
  • Stay hydrated and have some snacks handy. Cannabis can cause dry mouth, also known as cottonmouth, which can make you feel thirsty and uncomfortable. Drinking water or other non-alcoholic beverages can help you stay hydrated and prevent dehydration. Cannabis can also stimulate your appetite, also known as the munchies, which can make you crave food and eat more than usual. Having some healthy snacks available can help you satisfy your hunger and avoid overeating junk food45.
  • Enjoy the experience and have fun. Cannabis can enhance your senses, creativity, and mood, making you more aware of your surroundings, thoughts, and feelings. It can also help you relax, reduce stress, and relieve pain. Try to focus on the positive aspects of the experience and avoid negative thoughts or worries. You can also engage in activities that you enjoy, such as listening to music, watching a movie, playing a game, or having a conversation. Remember that the effects of cannabis are temporary and will wear off eventually, so there is no need to panic or be afraid45.

I hope this helps you prepare to use cannabis. 

MethodOnsetDuration
Smoking or vaping2–10 minutes1–4 hours
Edibles30–120 minutes4–24 hours
DabbingAlmost instant1–4 hours

If you want to end a high faster, you can try some of the following tips1:

  • Take a nap
  • Drink water or other non-alcoholic beverages
  • Have some healthy snacks
  • Be in a comfortable and safe environment
  • Avoid taking more cannabis until the effects wear off

However, these tips may only reduce the effects, not eliminate them completely. You should still avoid driving or operating heavy machinery until you are sober. If you experience any severe or unpleasant side effects, such as anxiety, paranoia, nausea, or chest pain, you should seek medical attention immediately.